3-Nitrophenol → HCID 18070177, compound

HRID 607293Notes

Reaction equation

HRID 607293 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([OH:10])[CH:7]=[CH:8][CH:9]=1)([O-])=O.[Br:11][C:12]1[CH:17]=[CH:16][C:15]([CH2:18]Br)=[CH:14][CH:13]=1.BrCC1C=CC=C(F)C=1>>[Br:11][C:12]1[CH:17]=[CH:16][C:15]([CH2:18][O:10][C:6]2[CH:5]=[C:4]([NH2:1])[CH:9]=[CH:8][CH:7]=2)=[CH:14][CH:13]=1

Participants

4

Reactant 3

HCID 111373-NitrophenolHCID 680073-Fluorobenzyl bromideHCID 685274-Bromobenzyl bromide

Product 1

HCID 18070177HCID 18070177, compound

Procedure

3-Nitro-phenol was reacted with 1-bromo-4-bromomethyl-benzene according to the procedure from Example 199A substituting 1-bromo-4-bromomethyl-benzene for 1-bromomethyl-3-fluoro-benzene then reduced according to the procedure from Example 199B to provide the title compound.

Sources & evidence

ORD record
ord-18c5ae27ea3243fcabd421174dc59a82
Source dataset
uspto-grants-2011_03
Patent number
US07915411B2

Reaction notes

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