Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-iodo-1H-imidazole → (S)-5-(1H-imidazol-2-ylethynyl)-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-iodo-1H-imidazole | HCID 2773468 | — |
| 반응물 | (S)-5-ethynyl-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24953136 | — |
| 생성물 | (S)-5-(1H-imidazol-2-ylethynyl)-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 86629468 | 29% |
반응 단계
In a manner similar to that describe in Example 434, a mixture of (S)-5-ethynyl-N-[methyl(oxo)phenyl-λ6-sulfanylidene]nicotinamide and 2-iodo-1H-imidazole were reacted to give the title compound as a white solid (15 mg, 29%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07915443B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-0069c148104348e7adccb155949eb00c |
| 출처 메모 | uspto-grants-2011_03 |