N-(3-ethynylphenyl)acetamide → (S)-5-{[3-(acetylamino)phenyl]ethynyl}-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide

Participants

Reaction Steps

In a manner similar to that described in Example 449, N-(3-ethynyl-phenyl)-acetamide (0.0469 g, 0.443 mmol) and (S)-5-bromo-N-[methyl(oxo)phenyl-λ6-sulfanylidene]nicotinamide (100 mg, 0.295 mmol) were reacted to give the title compound as a solid (83 mg, 0.20 mmol, 67%).

Provenance & Evidence