HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(4-Ethynylphenyl)-2,6-difluorobenzamide → HCID 24952782, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(4-Ethynylphenyl)-2,6-difluorobenzamide | HCID 3785792 | — |
| Reactant | (S)-5-bromo-N-[methyl(oxido)phenyl--sulfanylidene]nicotinamide | HCID 86629466 | — |
| Product | HCID 24952782 | HCID 24952782 | 74.3% |
Reaction Steps
In a manner similar to that described in Example 449, N-(4-ethynyl-phenyl)-2,6-difluoro-benzamide (0.114 g, 0.443 mmol) and (S)-5-bromo-N-[methyl(oxo)phenyl-λ6-sulfanylidene]nicotinamide (100 mg, 0.295 mmol) were reacted to give the title compound as a solid (113 mg, 74%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915443B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-d428bc96f0514fb0b728da3d0e25bae7 |
| Source note | uspto-grants-2011_03 |