HCID 57657837, compound → HCID 24955629, compound

HRID 607409Notes

Reaction equation

HRID 607409 reaction equation
Br[C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH:19]=1)[C:7]([N:9]=[S@@:10]([CH3:18])(=[O:17])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:8].[C:20]([C:22]1[CH:23]=[C:24]([CH:30]=[CH:31][CH:32]=1)[C:25]([NH:27][O:28][CH3:29])=[O:26])#[CH:21]>>[CH3:29][O:28][NH:27][C:25]([C:24]1[CH:23]=[C:22]([C:20]#[C:21][C:2]2[CH:3]=[N:4][CH:5]=[C:6]([CH:19]=2)[C:7]([N:9]=[S@@:10]([CH3:18])(=[O:17])[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:8])[CH:32]=[CH:31][CH:30]=1)=[O:26]

Participants

3

Reactant 2

HCID 57657837HCID 57657837, compoundHCID 86629466(S)-5-bromo-N-[methyl(oxido)phenyl--sulfanylidene]nicotinamide

Product 1

HCID 24955629HCID 24955629, compound

Procedure

In a manner similar to that described in Example 460 (step 2), (S)-5-bromo-N-[methyl(oxido)phenyl--sulfanylidene]nicotinamide (0.100 g, 0.295 mmol) and 3-Ethynyl-N-methoxy-benzamide (0.106 g, 0.442 mmol) were reacted to give the title compound yield (0.126 g, 86%).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-373592f50dff48749e406312c9c61829
Source dataset
uspto-grants-2011_03
Patent number
US07915443B2

Reaction notes

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