Methyl 3-{N-[(5-bromopyridin-3-yl)carbonyl]-S-methylsulfonimidoyl}benzoate → methyl 3-[N-({5-[(3-{[(1,3-dimethyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)ethynyl]pyridin-3-yl}carbonyl)-S-methylsulfonimidoyl]benzoate

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Methyl 3-{N-[(5-bromopyridin-3-yl)carbonyl]-S-methylsulfonimidoyl}benzoate	HCID 57657891	—
Edukt	N-(3-ethynylphenyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide	HCID 57657904	—
Produkt	methyl 3-[N-({5-[(3-{[(1,3-dimethyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)ethynyl]pyridin-3-yl}carbonyl)-S-methylsulfonimidoyl]benzoate	HCID 57657956	—

Reaktionsschritte

In a manner similar to that described in Example 460, methyl 3-{N-[(5-bromopyridin-3-yl)carbonyl]-S-methylsulfonimidoyl}benzoate and N-(3-ethynylphenyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide were reacted to give the title compound.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07915443B2
Quelldatensatz	uspto-grants-2011_03
ORD ID	ord-0aaa1abc07444e40a9fb8fa0c4fc8857
Quellennotiz	uspto-grants-2011_03