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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 607475Generated: October 30, 2026

Ethyl nipecotate → (S)-Ethyl 1-[(N-{[5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)pyridin-3-yl]carbonyl}-S-phenylsulfonimidoyl)acetyl]piperidine-3-carboxylate

https://huagongshe.com/reaction/607475

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl nipecotateHCID 98969—
Reactant(S)-ethyl(N-{[5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)pyridin-3-yl]carbonyl}-S-phenylsulfonimidoyl)acetateHCID 86629488—
Product(S)-Ethyl 1-[(N-{[5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)pyridin-3-yl]carbonyl}-S-phenylsulfonimidoyl)acetyl]piperidine-3-carboxylateHCID 86629491—

Reaction Steps

In a manner similar to that described in Example 534, (S)-Ethyl(N-{[5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)pyridin-3-yl]carbonyl}-S-phenylsulfonimidoyl)acetate and ethyl nipecotate were reacted to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07915443B2
Source datasetuspto-grants-2011_03
ORD IDord-f64a20744f0749c1887df9ccd4c7ac39
Source noteuspto-grants-2011_03