HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 607885Generated: October 29, 2026
4-Chloroanisole → Ethyl 4'-methoxy[1,1'-biphenyl]-4-carboxylate
https://huagongshe.com/reaction/607885
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Chloroanisole | HCID 12167 | — |
| Reactant | 4-Ethoxycarbonylphenylboronic acid | HCID 2734350 | — |
| Reagent | Water | HCID 962 | — |
| Reagent | Potassium Phosphate, Tribasic | HCID 62657 | — |
| Catalyst | Bis(1,5-cyclooctadiene)nickel | HCID 6433264 | — |
| Catalyst | HCID 121237543 | HCID 121237543 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | Ethyl 4'-methoxy[1,1'-biphenyl]-4-carboxylate | HCID 2764348 | 0% |
Reaction Steps
pre-ligate Ni(cod)2 and phosphine ligand in dioxane for 15 minutes in a separate plate
Provenance & Evidence
| DOI | 10.26434/chemrxiv.14388557.v1 |
|---|
| Source dataset | Ni-catalyzed Suzuki Miyaura cross-coupling |
|---|
| ORD ID | ord-9a70298ff3d44538a8aa2acb7a3d8eaa |
|---|
| Source note | Ni-catalyzed Suzuki Miyaura cross-coupling |
|---|
