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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 608087Generated: October 25, 2026

tert-Butyl (R)-3-(2-acetamidopropan-2-yl)-6-chloro-5-methyl-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylate → Biphenyl

https://huagongshe.com/reaction/608087

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl (R)-3-(2-acetamidopropan-2-yl)-6-chloro-5-methyl-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylateHCID 24805585—
Reactant3-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenolHCID 57443272—
CatalystHCID 178482905HCID 178482905—
SolventDimethyl SulfoxideHCID 679—
SolventWaterHCID 962—
ProductBiphenylHCID 7095—
Producttert-Butyl (R)-3-(2-acetamidopropan-2-yl)-6-chloro-5-methyl-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylateHCID 24805585—
ProductHCID 178474761HCID 178474761—
unknown2,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramineHCID 3393106—

Provenance & Evidence

DOI10.1038/s44160-023-00351-1
Source datasetCernak miniaturized Suzuki Cross-Coupling 12x10 Informer Library
ORD IDord-215c5c40671a4e338e28fca41226381e
Source noteCernak miniaturized Suzuki Cross-Coupling 12x10 Informer Library