2-methyl-4-phenyl-1,3-thiazole-5-carboxylic Acid → HCID 89739796, compound
Reaction equation
[CH3:1][O:2][C:3]1([O:13][CH3:14])[CH2:8][NH:7][CH:6]([C:9]([O:11][CH3:12])=[O:10])[CH2:5][CH2:4]1.[CH3:15][C:16]1[S:17][C:18]([C:27](O)=[O:28])=[C:19]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[N:20]=1>>[CH3:1][O:2][C:3]1([O:13][CH3:14])[CH2:8][N:7]([C:27]([C:18]2[S:17][C:16]([CH3:15])=[N:20][C:19]=2[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[O:28])[CH:6]([C:9]([O:11][CH3:12])=[O:10])[CH2:5][CH2:4]1Participants
3
Procedure
Methyl 5,5-dimethoxy-1-(2-methyl-4-phenylthiazole-5-carbonyl)piperidine-2-carboxylate was prepared according to general procedure A using methyl 5,5-dimethoxypiperidine-2-carboxylate and 2-methyl-4-phenylthiazole-5-carboxylic acid.
Sources & evidence
- ORD record
- ord-5723cad4562d4db7bfdd030de86326b0
- Source dataset
- uspto-grants-2016_09
- Patent number
- US09440982B2
Reaction notes
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