HRID60823

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6363

Isopropylamine

C3H9N

结构：Cc1nc(-c2ccccc2)c(C(=O)N2CC(=O)CCC2CNC(=O)c2cccc3cccnc23)s1

HCID89739420

未命名化合物

PRODUCTS

生成物

结构：Cc1nc(-c2ccccc2)c(C(=O)N2CC(NC(C)C)CCC2CNC(=O)c2cccc3cccnc23)s1

HCID89739393

未命名化合物

PROCEDURE

实验过程

N-((5-(Isopropylamino)-1-(2-methyl-4-phenylthiazole-5-carbonyl)piperidin-2-yl)methyl)quinoline-8-carboxamide was prepared according to general procedure N using N-((1-(2-methyl-4-phenylthiazole-5-carbonyl)-5-oxopiperidin-2-yl)methyl)quinoline-8-carboxamide and isopropyl amine. (ESI) 528 (M+H).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f1a4925a3f0a4c619ea7142a2d7a2add
来源数据集: uspto-grants-2016_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09440982B2
来源说明: uspto-grants-2016_09

反应 SMILES

[CH3:1][C:2]1[S:3][C:4]([C:13]([N:15]2[CH2:20][C:19](=O)[CH2:18][CH2:17][CH:16]2[CH2:22][NH:23][C:24]([C:26]2[CH:27]=[CH:28][CH:29]=[C:30]3[C:35]=2[N:34]=[CH:33][CH:32]=[CH:31]3)=[O:25])=[O:14])=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:6]=1.[CH:36]([NH2:39])([CH3:38])[CH3:37]>>[CH:36]([NH:39][CH:19]1[CH2:20][N:15]([C:13]([C:4]2[S:3][C:2]([CH3:1])=[N:6][C:5]=2[C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[O:14])[CH:16]([CH2:22][NH:23][C:24]([C:26]2[CH:27]=[CH:28][CH:29]=[C:30]3[C:35]=2[N:34]=[CH:33][CH:32]=[CH:31]3)=[O:25])[CH2:17][CH2:18]1)([CH3:38])[CH3:37]