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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 60828Generated: October 25, 2026

8-Quinolinecarboxylic acid → N-((1-(5-(3-Fluorophenyl)-2-methylthiazole-4-carbonyl)-5-methoxypiperidin-2-yl)methyl)quinoline-8-carboxamide

https://huagongshe.com/reaction/60828

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-Quinolinecarboxylic acidHCID 66582—
Reactant(2-(Aminomethyl)-5-methoxypiperidin-1-yl)(5-(3-fluorophenyl)-2-methylthiazol-4-yl)methanoneHCID 89739331—
ProductN-((1-(5-(3-Fluorophenyl)-2-methylthiazole-4-carbonyl)-5-methoxypiperidin-2-yl)methyl)quinoline-8-carboxamideHCID 71715334—

Reaction Steps

The title compound was prepared according to general procedure A using (2-(aminomethyl)-5-methoxypiperidin-1-yl)(5-(3-fluorophenyl)-2-methylthiazol-4-yl)methanone and quinoline-8-carboxylic acid. (ESI) 519 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-94fb3b1ecc2e44388d79f38f8bffef69
Source noteuspto-grants-2016_09