2-methyl-4-phenyl-1,3-thiazole-5-carboxylic Acid → Ethyl 2-(2-(2-methyl-4-phenylthiazole-5-carbonyl)octahydro-1H-isoindol-1-yl)acetate

HRID 60836Notes

Reaction equation

HRID 60836 reaction equation
[CH:1]1([CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:9]2[CH:4]([CH2:5][CH2:6][CH2:7][CH2:8]2)[CH2:3][NH:2]1.[CH3:16][C:17]1[S:18][C:19]([C:28](O)=[O:29])=[C:20]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[N:21]=1>>[CH3:16][C:17]1[S:18][C:19]([C:28]([N:2]2[CH2:3][CH:4]3[CH:9]([CH2:8][CH2:7][CH2:6][CH2:5]3)[CH:1]2[CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=[O:29])=[C:20]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[N:21]=1

Participants

3

Reactant 2

HCID 71311322-methyl-4-phenyl-1,3-thiazole-5-carboxylic AcidHCID 89740797Octahydro-1H-isoindole-1-acetic acid ethyl ester

Product 1

HCID 89739325Ethyl 2-(2-(2-methyl-4-phenylthiazole-5-carbonyl)octahydro-1H-isoindol-1-yl)acetate

Procedure

Ethyl 2-(2-(2-methyl-4-phenylthiazole-5-carbonyl)octahydro-1H-isoindol-1-yl)acetate was prepared according general procedure A from ethyl 2-(octahydro-1H-isoindol-1-yl)acetate and 2-methyl-4-phenylthiazole-5-carboxylic acid.

Sources & evidence

ORD record
ord-ad22b6a29e5b4db991b17084da2a7937
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Reaction notes

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