HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-5-methylbenzoic acid → rac-cis-(2-(Aminomethyl)-3-methylpiperidin-1-yl)(2-bromo-5-methylphenyl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-5-methylbenzoic acid | HCID 228080 | — |
| Reactant | cis-N-Boc-1-(3-methylpiperidin-2-YL)methanamine | HCID 95378400 | — |
| Product | rac-cis-(2-(Aminomethyl)-3-methylpiperidin-1-yl)(2-bromo-5-methylphenyl)methanone | HCID 131737146 | — |
Reaction Steps
The title compound was synthesized following the same general protocol as described in Example 11 using rac-cis-tert-butyl ((3-methylpiperidin-2-yl)methyl)carbamate and 2-bromo-5-methylbenzoic acid. ESI-MS (m/z): 325, 327, [M]+, [M+2]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09440982B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-e5c8f0cc12d34483939a84bf0561aee4 |
| Source note | uspto-grants-2016_09 |