HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(1H-imidazol-1-yl)-5-methylbenzoic acid → rac-cis-(2-(1H-Imidazol-1-yl)-5-methylphenyl)(3-methyl-2-(((5-(trifluoromethyl)pyridin-2-yl)amino)methyl)piperidin-1-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(1H-imidazol-1-yl)-5-methylbenzoic acid | HCID 54592928 | — |
| Reactant | rac-cis-N-((3-Methylpiperidin-2-yl)methyl)-5-(trifluoromethyl)pyridin-2-amine | HCID 131737152 | — |
| Product | rac-cis-(2-(1H-Imidazol-1-yl)-5-methylphenyl)(3-methyl-2-(((5-(trifluoromethyl)pyridin-2-yl)amino)methyl)piperidin-1-yl)methanone | HCID 131737155 | — |
Reaction Steps
The title compound was synthesized following the same general protocol as described in Example 11 using 2-(1H-imidazol-1-yl)-5-methylbenzoic acid and rac-cis-N-((3-methylpiperidin-2-yl)methyl)-5-(trifluoromethyl)pyridin-2-amine. ESI-MS (m/z): 458, [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09440982B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-1e3acad0b6f840e9af101307e8be9443 |
| Source note | uspto-grants-2016_09 |