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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 609015Generated: October 29, 2026

5-bromo-N-(4-fluorobenzyl)-8-hydroxy-1,6-naphthyridine-7-carboxamide → Biphenyl

https://huagongshe.com/reaction/609015

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-bromo-N-(4-fluorobenzyl)-8-hydroxy-1,6-naphthyridine-7-carboxamideHCID 22346401—
Reactant1-(Phenylsulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrolo[2,3-b]pyridineHCID 45588137—
CatalystHCID 178454896HCID 178454896—
SolventDimethyl SulfoxideHCID 679—
SolventWaterHCID 962—
Solvent2-Methyl-2-butanolHCID 6405—
ProductBiphenylHCID 7095—
Product5-bromo-N-(4-fluorobenzyl)-8-hydroxy-1,6-naphthyridine-7-carboxamideHCID 22346401—
ProductHCID 178523003HCID 178523003—
unknown2-tert-Butyl-1,1,3,3-tetramethylguanidineHCID 3571581—

Provenance & Evidence

DOI10.1038/s44160-023-00351-1
Source datasetCernak miniaturized Suzuki Cross-Coupling 12x10 Informer Library
ORD IDord-58bfd012518f4d93a0a36317f344cdf7
Source noteCernak miniaturized Suzuki Cross-Coupling 12x10 Informer Library