4-Methylpyridine-3-Boronic Acid → 5-Methyl-2-(4-methylpyridin-3-yl)benzoic acid

HRID 60905Notes

Reaction equation

HRID 60905 reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][C:5](C2C=NN(C)C=2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8].[CH3:17][C:18]1[CH:23]=[CH:22][N:21]=[CH:20][C:19]=1B(O)O>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:19]2[CH:20]=[N:21][CH:22]=[CH:23][C:18]=2[CH3:17])=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8]

Participants

3

Reactant 2

HCID 27627114-Methylpyridine-3-Boronic AcidHCID 811115005-Methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoic acid

Product 1

HCID 811120035-Methyl-2-(4-methylpyridin-3-yl)benzoic acid

Procedure

The title compound was synthesized following the same general protocol as described for 5-methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoic acid in Example A1, using (4-methylpyridin-3-yl)boronic acid. ESI-MS (m/z): 228 [M+1]+.

Sources & evidence

ORD record
ord-fa732bf5f5ab4cf9ad07521a517ddebd
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Reaction notes

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