Methyl 5-methyl-2-(pyridin-2-yl)benzoate → (5-Methyl-2-(pyridin-2-yl)phenyl)carboxylic acid

HRID 60908Notes

Reaction equation

HRID 60908 reaction equation
CC1C=CC(C2C=NN(C)C=2)=C(C=1)C(O)=O.[CH3:17][C:18]1[CH:19]=[CH:20][C:21]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][N:29]=2)=[C:22]([CH:27]=1)[C:23]([O:25]C)=[O:24]>>[CH3:17][C:18]1[CH:19]=[CH:20][C:21]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][N:29]=2)=[C:22]([CH:27]=1)[C:23]([OH:25])=[O:24]

Participants

3

Reactant 2

HCID 67982793Methyl 5-methyl-2-(pyridin-2-yl)benzoateHCID 811115005-Methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoic acid

Product 1

HCID 67982743(5-Methyl-2-(pyridin-2-yl)phenyl)carboxylic acid

Procedure

The title compound was synthesized following the same general protocol as described for 5-methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoic acid in Example A1, using methyl 5-methyl-2-(pyridin-2-yl)benzoate. ESI-MS (m/z): 214 [M+1]+.

Sources & evidence

ORD record
ord-0afb86e245cd4447b51de6db04c324c3
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Reaction notes

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