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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 60925Generated: October 25, 2026

2-Chloro-4-methoxypyrimidine → 2-(4-Methoxy-2-pyrimidinyl)-5-methylbenzoic acid

https://huagongshe.com/reaction/60925

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-methoxypyrimidineHCID 588935—
Reactant5-Methyl-2-(2-pyrazinyl)benzoic acidHCID 81111608—
Product2-(4-Methoxy-2-pyrimidinyl)-5-methylbenzoic acidHCID 117727863—

Reaction Steps

The title compound was prepared following the same general protocol as described for 5-methyl-2-(pyrazin-2-yl)benzoic acid in Example A19, starting from 2-chloro-4-methoxypyrimidine. ESI-MS (m/z): 245 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-5a715927cf5b4426a72171e2e0f791ae
Source noteuspto-grants-2016_09