1H-1,2,4-Triazole → 5-methyl-2-(1H-1,2,4-triazol-1-yl)benzoic acid

HRID 60941Notes

Reaction equation

HRID 60941 reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N:11]2[N:15]=[CH:14]C=N2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8].[NH:16]1[CH:20]=NC=N1>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N:11]2[CH:20]=[N:16][CH:14]=[N:15]2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8]

Participants

3

Reactant 2

HCID 92571H-1,2,4-TriazoleHCID 532601655-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid

Product 1

HCID 625146105-methyl-2-(1H-1,2,4-triazol-1-yl)benzoic acid

Procedure

The title compound was synthesized following the same general protocol as described for 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid in Example A11 using 1H-1,2,4-triazole. ESI-MS (m/z): 204 [M+1]+.

Sources & evidence

ORD record
ord-3e825d5307b540d1b2e4257af17db1a1
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Reaction notes

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