5-Chloro-N-(((2S,3R)-3-methylpiperidin-2-yl)methyl)benzo[d]oxazol-2-amine → HCID 89748175, compound

HRID 60943Notes

Reaction equation

HRID 60943 reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N:11]2[CH:15]=[N:14][C:13]([CH3:16])=[N:12]2)=[C:6]([CH:10]=1)[C:7]([OH:9])=O.[Cl:17][C:18]1[CH:19]=[CH:20][C:21]2[O:25][C:24]([NH:26][CH2:27][C@@H:28]3[C@H:33]([CH3:34])[CH2:32][CH2:31][CH2:30][NH:29]3)=[N:23][C:22]=2[CH:35]=1>>[Cl:17][C:18]1[CH:19]=[CH:20][C:21]2[O:25][C:24]([NH:26][CH2:27][C@@H:28]3[C@H:33]([CH3:34])[CH2:32][CH2:31][CH2:30][N:29]3[C:7]([C:6]3[CH:10]=[C:2]([CH3:1])[CH:3]=[CH:4][C:5]=3[N:11]3[CH:15]=[N:14][C:13]([CH3:16])=[N:12]3)=[O:9])=[N:23][C:22]=2[CH:35]=1

Participants

3

Reactant 2

HCID 1177280155-Chloro-N-(((2S,3R)-3-methylpiperidin-2-yl)methyl)benzo[d]oxazol-2-amineHCID 1177281205-methyl-2-(3-methyl-1H-1,2,4-triazol-1-yl)benzoic acid

Product 1

HCID 89748175HCID 89748175, compound

Procedure

The title compound was prepared following the same general protocol as described in Example A1, using 5-methyl-2-(3-methyl-1H-1,2,4-triazol-1-yl)benzoic acid and 5-chloro-N-(((2S,3R)-3-methylpiperidin-2-yl)methyl)benzo[d]oxazol-2-amine. ESI-MS (m/z): 479 [M+1]+.

Sources & evidence

ORD record
ord-fa9f4c7adf944effb84511688d3dbecb
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Reaction notes

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