Imidazole → 2-(1H-imidazol-1-yl)-5-methylbenzoic acid

HRID 60948Notes

Reaction equation

HRID 60948 reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N:11]2N=CC=N2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8].[NH:16]1[CH:20]=[CH:19]N=[CH:17]1>>[N:11]1([C:5]2[CH:4]=[CH:3][C:2]([CH3:1])=[CH:10][C:6]=2[C:7]([OH:9])=[O:8])[CH:19]=[CH:20][N:16]=[CH:17]1

Participants

3

Reactant 2

HCID 795ImidazoleHCID 532601655-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid

Product 1

HCID 545929282-(1H-imidazol-1-yl)-5-methylbenzoic acid

Procedure

The title compound was synthesized following the same general protocol as described for 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid in Example A11, using imidazole. ESI-MS (m/z): 203 [M+1]+.

Sources & evidence

ORD record
ord-5e3cf232c47744dba7bbbd53b0cc25b8
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Reaction notes

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