Ammonia → Glyphosate

HRID 609535Notes

Reaction equation

HRID 609535 reaction equation
[CH2:1]([NH:5][CH2:6][P:7]([OH:10])([OH:9])=[O:8])[C:2]([OH:4])=[O:3].[NH3:11]>O>[CH2:1]([NH:5][CH2:6][PH2:7])[C:2]([O-:4])=[O:3].[NH4+:11].[CH2:1]([NH:5][CH2:6][P:7]([OH:10])([OH:9])=[O:8])[C:2]([OH:4])=[O:3]

Participants

5

Reactant 2

HCID 222Ammonia2×HCID 3496Glyphosate

Product 2

HCID 3496GlyphosateHCID 44152490HCID 44152490, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

In a stirred 10 liter round-bottom flask equipped with a water cooled condenser, thermometer, nitrogen blanket and equilibrating dropping funnel, was charged 500 grams of Solution 1 and 968 grams of water. With stirring, 2409 grams of glyphosate acid in the form of wet cake were added. Then 1623 grams of 25% aqueous ammonia were added at such a rate that the temperature of reaction mixture did not exceed 85° C. The pH of the reaction mixture was measured, and up to 85 grams of 25% aqueous ammonia were added in increments until a pH of 6.3-6.7 was obtained. The assay was determined by high pressure liquid chromatography by standard methods and sufficient additional water added to give an ammonium glyphosate solution with a glyphosate assay of 41.7% a.e. or 525 g a.e./l.

Workup

  1. customIn a stirred 10 liter round-bottom flask equipped with a water cooled condenser
  2. customthat the temperature of reaction mixture
  3. customdid not exceed 85° C
  4. customwas obtained
  5. additionadded

Sources & evidence

ORD record
ord-36d1ea93fb564ca2a2e770fd879a0244
Source dataset
uspto-grants-1999_12
Patent number
US05998332

Reaction notes

Loading…