2-Methylpyridine-5-boronic acid → 5-Methyl-2-(6-methylpyridin-3-yl)benzoic acid

HRID 60957Notes

Reaction equation

HRID 60957 reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][C:5](C2C=NN(C)C=2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8].[CH3:17][C:18]1[N:23]=[CH:22][C:21](B(O)O)=[CH:20][CH:19]=1>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:21]2[CH:22]=[N:23][C:18]([CH3:17])=[CH:19][CH:20]=2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8]

Participants

3

Reactant 2

HCID 27630812-Methylpyridine-5-boronic acidHCID 811115005-Methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoic acid

Product 1

HCID 811127655-Methyl-2-(6-methylpyridin-3-yl)benzoic acid

Procedure

The title compound was synthesized following the same general protocol as described for 5-methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoic acid in Example A1, using (6-methylpyridin-3-yl)boronic acid. ESI-MS (m/z): 228 [M+1]+.

Sources & evidence

ORD record
ord-ddd0efd0de8e4340b714a3cfed924ba9
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Reaction notes

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