Ammonia → Thourea, (4-chlorophenyl)- (9CI)

HRID 609570Notes

Reaction equation

HRID 609570 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]=[C:9]=[S:10])=[CH:4][CH:3]=1.[NH3:11]>CCOCC>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([NH2:11])=[S:10])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 164804-Chlorophenyl isothiocyanate

Product 1

HCID 735843Thourea, (4-chlorophenyl)- (9CI)

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A stirred solution of 4-chlorophenyl isothiocyanate (10.0 g, 0.077 mol) in 100 ml ether was saturated with ammonia gas for five minutes. The reaction mixture was then stirred for 18 hr. The white solid which precipitated was collected by filtration and yielded 6.3 g of N-(4-chlorophenyl)thiourea, M.P. 147-148° C.

Workup

  1. customThe white solid which precipitated
  2. filtrationwas collected by filtration

Sources & evidence

ORD record
ord-3d7718d143754524908a18bdbe2da2b7
Source dataset
uspto-grants-1999_12
Patent number
US05998399

Reaction notes

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