1-(Bromomethyl)-4-chlorobenzene → 2-[4-(3-Methoxybenzyl)-1-piperazinyl]-2,4,6-cycloheptatriene-1-one

HRID 609586Notes

Reaction equation

HRID 609586 reaction equation
Br[C:2]1[C:8](=[O:9])[C:7]([N:10]2[CH2:15][CH2:14][N:13]([CH2:16][C:17]3[CH:22]=[CH:21][C:20](Cl)=[CH:19][CH:18]=3)[CH2:12][CH2:11]2)=[CH:6][CH:5]=[CH:4][CH:3]=1.BrC1[C:31](=[O:32])C(N2CCNCC2)=CC=CC=1.ClC1C=CC(CBr)=CC=1>>[CH3:31][O:32][C:19]1[CH:18]=[C:17]([CH:22]=[CH:21][CH:20]=1)[CH2:16][N:13]1[CH2:14][CH2:15][N:10]([C:7]2[C:8](=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 693291-(Bromomethyl)-4-chlorobenzeneHCID 195997127-Bromo-2-[4-(4-chlorobenzyl)-1-piperazinyl]-2,4,6-cycloheptatriene-1-oneHCID 195997157-Bromo-2-(1-piperazinyl)-2,4,6-cycloheptatriene-1-one

Product 1

HCID 158713422-[4-(3-Methoxybenzyl)-1-piperazinyl]-2,4,6-cycloheptatriene-1-one

Procedure

7-bromo-2-[4-(4-chlorobenzyl)-1-piperazinyl]-2,4,6-cycloheptatriene-1-one, from 7-bromo-2-(1-piperazinyl)-2,4,6-cycloheptatriene-1-one of example 2b and 4-chlorobenzyl bromide.

Sources & evidence

ORD record
ord-3b2e5b94a50246f68ea55149dc55615d
Source dataset
uspto-grants-1999_12
Patent number
US05998414

Reaction notes

Loading…