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1H-Indole-3-carboxylic acid, 2-chloro- → N-[(1-n butyl-4-piperidyl)methyl]2-chloroindole-3-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1H-Indole-3-carboxylic acid, 2-chloro- | HCID 99521 | — |
| 反応物 | N-[(1-n butyl-4-piperidyl)methyl] indole-3-carboxamide | HCID 10591304 | — |
| 生成物 | N-[(1-n butyl-4-piperidyl)methyl]2-chloroindole-3-carboxamide | HCID 22096969 | — |
反応手順
2-Chloroindole-3-carboxylic acid (L. Marchetti and A Andreani, Ann. Chim. (Rome), 1973, 63, 681) was converted to its acid chloride and reacted with N-(1-n butyl-4-piperidyl)methylamine (D1) using the procedure of Description 1b to afford N-[(1-n butyl-4-piperidyl)methyl]2-chloroindole-3-carboxamide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05998409 |
| 出典データセット | uspto-grants-1999_12 |
| ORD ID | ord-a21d3270672b4aa1a7ed054c7bdf51f9 |
| 出典メモ | uspto-grants-1999_12 |