HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole-3-Carboxylic Acid → N-[(1-Methyl-4-piperidyl)methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole-3-Carboxylic Acid | HCID 69867 | — |
| Reactant | 1-Methylpiperidine-4-methylamine | HCID 81574 | — |
| Reactant | N-[(1-n butyl-4-piperidyl)methyl] indole-3-carboxamide | HCID 10591304 | — |
| Product | N-[(1-Methyl-4-piperidyl)methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide | HCID 19599445 | — |
| Product | N-[(1-Methyl-4-piperidyl)methyl] indole-3-carboxamide | HCID 19599451 | — |
Reaction Steps
N-[(1-Methyl-4-piperidyl)methyl]indole-3-carboxamide was prepared from indole-3-carboxylic acid and N-(1-methyl-4-piperidyl)methylamine using an analogous method to Description 1b and then converted to the title compound using an similar procedure to Example 3 (method 2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05998409 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-40dee26818a24ab9b1c5fb4a1554a93e |
| Source note | uspto-grants-1999_12 |