HCID 18396100, compound → HCID 19600424, compound

HRID 609741Notes

Reaction equation

HRID 609741 reaction equation
BrC1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11](=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH:6]=[C:5]2[CH2:19][CH2:20][N:21]1[CH2:25]C[CH2:23][CH2:22]1.C([Sn](CCCC)(CCCC)[C:31]1[O:32][C@H:33]([CH2:43]OOC)[C@@H:34](OOC)[C@H:35](OOC)[CH:36]=1)CCC>>[O:32]1[CH:31]=[CH:36][CH2:35][CH2:34][CH:33]1[C:43]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11](=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH:6]=[C:5]2[CH:19]1[CH2:23][CH2:22][N:21]([CH3:25])[CH2:20]1

Participants

3

Reactant 2

HCID 18396100HCID 18396100, compoundHCID 57187752HCID 57187752, compound

Product 1

HCID 19600424HCID 19600424, compound

Procedure

3-(2-Pyrrolidinylethyl)-5-(3,4,6-trimethoxyglucal-1-yl)-1-benzoylindole: (80%), from 5-bromo-3-(2-pyrrolidinylethyl)-1-benzoylindole (Example 5c) and 2-tributylstannyl-tri-O-methoxy-D-glucal (Example 8).

Sources & evidence

ORD record
ord-5ed9bc80e9a94ee4894facbb12a2655c
Source dataset
uspto-grants-1999_12
Patent number
US05998438

Reaction notes

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