HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2,2,2-Trifluoroethoxy)ethan-1-ol → 1-(t-butoxycarbonyl)-4-(1-(2-(2,2,2-trifluoroethoxy)ethyl)-1H-benzimidazole-2-carbonyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2,2,2-Trifluoroethoxy)ethan-1-ol | HCID 255854 | — |
| Reactant | 1-(t-butoxycarbonyl)-4-(1H-benzimidazole-2-carbonyl)piperidine | HCID 18333235 | — |
| Product | 1-(t-butoxycarbonyl)-4-(1-(2-(2,2,2-trifluoroethoxy)ethyl)-1H-benzimidazole-2-carbonyl)piperidine | HCID 21697352 | — |
Reaction Steps
Prepare by the method of Preparation 9 using 2-hydroxyethyl 2,2,2-trifluorethyl ether and 1-(t-butoxycarbonyl)-4-(1H-benzimidazole-2-carbonyl)piperidine (2.0 g, 6.1 mmol) to give 1-(t-butoxycarbonyl)-4-(1-(2-(2,2,2-trifluoroethoxy)ethyl)-1H-benzimidazole-2-carbonyl)piperidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05998439 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-d1b39b821be345fda6290f8c83cbc400 |
| Source note | uspto-grants-1999_12 |