Benzyl Bromide → 1-Benzyl-2-(((tert-Butoxycarbonyl)amino)methyl)-3-methylpyridin-1-ium bromide

Participants

Reaction Steps

A solution of tert-butyl ((3-methylpyridin-2-yl)methyl)carbamate (9.2 g, 41 mmol) and benzyl bromide (9.9 mL, 83 mmol) in 150 ml of acetonitrile was heated in a sealed vessel at reflux overnight and then concentrated in vacuo to give the title compound which was used without further purification. MS (ESI) 313 (M+H).

Provenance & Evidence