2,5-Dichlorobenzooxazole → (1-(((5-Chlorobenzo[d]oxazol-2-yl)amino)methyl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone

HRID 60998Notes

Reaction equation

HRID 60998 reaction equation
[NH2:1][CH2:2][CH:3]1[CH:7]2[CH2:8][CH2:9][CH2:10][CH:6]2[CH2:5][N:4]1[C:11]([C:13]1[CH:18]=[C:17]([CH3:19])[CH:16]=[CH:15][C:14]=1[N:20]1[N:24]=[CH:23][CH:22]=[N:21]1)=[O:12].Cl[C:26]1[O:27][C:28]2[CH:34]=[CH:33][C:32]([Cl:35])=[CH:31][C:29]=2[N:30]=1>>[Cl:35][C:32]1[CH:33]=[CH:34][C:28]2[O:27][C:26]([NH:1][CH2:2][CH:3]3[CH:7]4[CH2:8][CH2:9][CH2:10][CH:6]4[CH2:5][N:4]3[C:11]([C:13]3[CH:18]=[C:17]([CH3:19])[CH:16]=[CH:15][C:14]=3[N:20]3[N:24]=[CH:23][CH:22]=[N:21]3)=[O:12])=[N:30][C:29]=2[CH:31]=1

Participants

3

Reactant 2

HCID 103975782,5-DichlorobenzooxazoleHCID 117727999(1-(Aminomethyl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone

Product 1

HCID 117727661(1-(((5-Chlorobenzo[d]oxazol-2-yl)amino)methyl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone

Procedure

The title compound was prepared following the same general protocol as described for Example A2 using (1-(aminomethyl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone and 2,5-dichlorobenzoxazole. MS (ESI) 477 (M+H).

Sources & evidence

ORD record
ord-a649eca765134c749a1a8444db35bab3
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Reaction notes

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