HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → 3-(4-Fluorophenyl)-6-methylpicolinonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 2760593 | — |
| Reactant | 3-Bromo-6-methylpyridine-2-carbonitrile | HCID 21952747 | — |
| Reactant | Methyl 5-methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoate | HCID 117727848 | — |
| Product | 3-(4-Fluorophenyl)-6-methylpicolinonitrile | HCID 117727830 | — |
Reaction Steps
The title compound was synthesized following the same general protocol as described for methyl 5-methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoate in Example A1, using 2-(4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane and 3-bromo-6-methylpicolinonitrile. ESI-MS (m/z): 213 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09440982B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-86edf712a7304eca955bf69d34893632 |
| Source note | uspto-grants-2016_09 |