Methyl Isocyanate → HCID 18782985, compound

HRID 610036Notes

Reaction equation

HRID 610036 reaction equation
Cl.[C:2]1([CH2:15][CH2:16][NH2:17])[C:6]2=[C:7]3[C:12](=[CH:13][CH:14]=[C:5]2[O:4][CH:3]=1)[O:11][CH2:10][CH2:9][CH2:8]3.[CH3:18][N:19]=[C:20]=[O:21]>N1C=CC=CC=1>[C:2]1([CH2:15][CH2:16][NH:17][C:20]([NH:19][CH3:18])=[O:21])[C:6]2=[C:7]3[C:12](=[CH:13][CH:14]=[C:5]2[O:4][CH:3]=1)[O:11][CH2:10][CH2:9][CH2:8]3

Participants

4

Reactant 2

HCID 12228Methyl IsocyanateHCID 18783036HCID 18783036, compound

Product 1

HCID 18782985HCID 18782985, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

To a suspension of 0.01 mole of 2-(8,9-dihydro-7H-furo[3,2-f]chromen-1-yl)ethylamine hydrochloride in five (5) ml of pyridine, 0.011 mole of methylisocyanate is added dropwise with stirring. The reaction mixture is stirred for one (1) hour at 80° C., then poured on ice/water. After classical work up and purification, the title compound is obtained.

Workup

  1. additionis added dropwise
  2. additionpoured on ice/water
  3. customAfter classical work up and purification

Sources & evidence

ORD record
ord-62791f73bf0b4ca1b6fffa8c12c90f0f
Source dataset
uspto-grants-1999_12
Patent number
US05998461

Reaction notes

Loading…