5-Sec-butyl-1-trifluoroacetylindole → 5-Isopropyl-1-trifluoroacetylindole

HRID 610051Notes

Reaction equation

HRID 610051 reaction equation
[CH:1]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[N:10]([C:14](=[O:19])[C:15]([F:18])([F:17])[F:16])[CH:9]=[CH:8]2)([CH2:3]C)[CH3:2].C(C1C=CC(NCC(OCC)OCC)=CC=1)(CC)C>>[CH:1]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[N:10]([C:14](=[O:19])[C:15]([F:16])([F:17])[F:18])[CH:9]=[CH:8]2)([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 196009505-Sec-butyl-1-trifluoroacetylindoleHCID 196009634-Sec-butyl-N-(2,2-diethoxyethyl)aniline

Product 1

HCID 105629375-Isopropyl-1-trifluoroacetylindole

Procedure

5-Sec-butyl-1-trifluoroacetylindole; from 4-sec-butyl-N-(2,2-diethoxyethyl) aniline (Example 1c) (18%).

Sources & evidence

ORD record
ord-01cf5c737d0e4a7dabb6b604e31170a2
Source dataset
uspto-grants-1999_12
Patent number
US05998462

Reaction notes

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