HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-amino-N-(4-chlorophenyl)benzamide → 5-Acetyl-1-ethyl-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid [3-(4-chloro-phenylcarbamoyl)-phenyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-amino-N-(4-chlorophenyl)benzamide | HCID 16780987 | — |
| Reactant | 1-ethyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid methyl ester | HCID 53893352 | — |
| Product | 5-Acetyl-1-ethyl-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid [3-(4-chloro-phenylcarbamoyl)-phenyl]-amide | HCID 9869562 | — |
Reaction Steps
Prepared as in Example 1 from 1-ethyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid methyl ester and 3-amino-N-(4-chloro-phenyl)-benzamide. Recrystallized from ethyl acetate-hexanes. mp 119-121° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05998463 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-ffa5ba5494474dc2ae99917e126f5cab |
| Source note | uspto-grants-1999_12 |