HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-amino-N-(3-fluorophenyl)benzamide → 5-Acetyl-1-ethyl-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid [3-(3-fluoro-phenylcarbamoyl)-phenyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-amino-N-(3-fluorophenyl)benzamide | HCID 16793933 | — |
| Reactant | 1-ethyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid methyl ester | HCID 53893352 | — |
| Product | 5-Acetyl-1-ethyl-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid [3-(3-fluoro-phenylcarbamoyl)-phenyl]-amide | HCID 9825437 | — |
Reaction Steps
Prepared as in Example 1 from 1-ethyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid methyl ester and 3-amino-N-(3-fluoro-phenyl)-benzamide. 1H NMR (CDCl3) δ 1.25 (t, 3 H), 2.6 (s, 3 H), 3.85 (q, 2 H), 4.45 (s, 1 H), 6.85-8.05 (m, 11 H), 8.3 (s, 1 H), 9.65 (s, 1 H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05998463 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-768880f1924a44bda835561914293481 |
| Source note | uspto-grants-1999_12 |