Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 610065Generated: October 27, 2026

3-Amino-N-(4-bromophenyl)benzamide → 5-Acetyl-1-ethyl-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid [3-(4-bromo-phenylcarbamoyl)-phenyl]-amide

https://huagongshe.com/reaction/610065

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-N-(4-bromophenyl)benzamideHCID 13609514—
Reactant1-ethyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid methyl esterHCID 53893352—
Product5-Acetyl-1-ethyl-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid [3-(4-bromo-phenylcarbamoyl)-phenyl]-amideHCID 9806709—

Reaction Steps

Prepared as in Example 1 from 1-ethyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid methyl ester and 3-amino-N-(4-bromo-phenyl)-benzamide. mp 117-120° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05998463
Source datasetuspto-grants-1999_12
ORD IDord-549cd0c6ab714dfda38c67b932846e4b
Source noteuspto-grants-1999_12