HRID610067

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID84347

Benzamide, 3-amino-N-phenyl-

C13H12N2O

结构：CCOC(=O)C1C(=O)N(CC)c2ccc(C(=O)c3ccccc3)cc21

HCID20189466

未命名化合物

PRODUCTS

生成物

结构：CCN1C(=O)C(C(=O)Nc2cccc(C(=O)Nc3ccccc3)c2)c2cc(C(=O)c3ccccc3)ccc21

HCID54572825

未命名化合物

PROCEDURE

实验过程

Prepared as in Example 1, Step A, from 5-benzoyl-1-ethyl-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid ethyl ester (U.S. Pat. No. 4,686,224) and 3-amino-N-phenyl-benzamide. Purified by trituration in ethyl acetate/hexanes. mp 129-135° C.

WORKUP

后处理

customPrepared as in Example 1, Step A
customPurified by trituration in ethyl acetate/hexanes

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-06bff11b701640128bcbb32f0cef2f6f
来源数据集: uspto-grants-1999_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05998463
来源说明: uspto-grants-1999_12

反应 SMILES

C([O:3][C:4]([CH:6]1[C:14]2[C:9](=[CH:10][CH:11]=[C:12]([C:15](=[O:22])[C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH:13]=2)[N:8]([CH2:23][CH3:24])[C:7]1=[O:25])=O)C.[NH2:26][C:27]1[CH:28]=[C:29]([CH:39]=[CH:40][CH:41]=1)[C:30]([NH:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)=[O:31]>>[C:33]1([NH:32][C:30]([C:29]2[CH:28]=[C:27]([NH:26][C:4]([CH:6]3[C:14]4[C:9](=[CH:10][CH:11]=[C:12]([C:15](=[O:22])[C:16]5[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=5)[CH:13]=4)[N:8]([CH2:23][CH3:24])[C:7]3=[O:25])=[O:3])[CH:41]=[CH:40][CH:39]=2)=[O:31])[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1