HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-N-(4-bromophenyl)benzamide → 5-Acetyl-1-methyl-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid [3-(4-bromo-penylcarbamoyl)-phenyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-N-(4-bromophenyl)benzamide | HCID 13609514 | — |
| Reactant | 1-methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid methyl ester | HCID 53966685 | — |
| Product | 5-Acetyl-1-methyl-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid [3-(4-bromo-penylcarbamoyl)-phenyl]-amide | HCID 10207526 | — |
Reaction Steps
Prepared as in Example 1 from 1-methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid methyl ester and 3-amino-N-(4-bromo-phenyl)-benzamide. Purified by flash-chromatography (hexanes/acetone, 1:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05998463 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-7f072b296ace4bb2ad55cee16defa987 |
| Source note | uspto-grants-1999_12 |