4-Bromo-2-fluoroaniline → 2-Iodo-4-(2-aminosulfonylphenyl)aniline

HRID 610108Notes

Reaction equation

HRID 610108 reaction equation
F[C:2]1[CH:8]=[C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[S:15]([NH2:18])(=[O:17])=[O:16])[CH:6]=[CH:5][C:3]=1[NH2:4].[I:19]C1C=C(Br)C=CC=1N.FC1C=C(Br)C=CC=1N>>[I:19][C:2]1[CH:8]=[C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[S:15]([NH2:18])(=[O:17])=[O:16])[CH:6]=[CH:5][C:3]=1[NH2:4]

Participants

4

Reactant 3

HCID 1230504-Bromo-2-fluoroanilineHCID 8239344-Bromo-2-iodoanilineHCID 181773022-Fluoro-4-(2-aminosulfonylphenyl)aniline

Product 1

HCID 181773162-Iodo-4-(2-aminosulfonylphenyl)aniline

Procedure

This compound was prepared by the method described for 2-fluoro-4-(2 -aminosulfonylphenyl)aniline described in EXAMPLE 8 by starting with 2-iodo-4-bromoaniline rather than 2-fluoro-4 -bromoaniline.

Workup

  1. customThis compound was prepared by the method

Sources & evidence

ORD record
ord-92ce651bd2db45f092193d49aeebe6fd
Source dataset
uspto-grants-1999_12
Patent number
US05998424

Reaction notes

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