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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 61020Generated: October 30, 2026

2-Chloronicotinonitrile → HCID 117727691, compound

https://huagongshe.com/reaction/61020

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChloronicotinonitrileHCID 81079—
Reactantrac-((2S,3R)-3-methyl-2-(((5-(trifluoromethyl)pyridin-2-yl)amino)methyl)piperidin-1-yl)(5-methyl-2-(1-methyl-1H-pyrazol-4-yl)phenyl)methanoneHCID 89748276—
ProductHCID 117727691HCID 117727691—

Reaction Steps

The title compound was synthesized following the same general protocol as described for ((2S,3R)-3-methyl-2-(((5-(trifluoromethyl)pyridin-2-yl)amino)methyl)piperidin-1-yl)(5-methyl-2-(1-methyl-1H-pyrazol-4-yl)phenyl)methanone in Example A1, using 2-chloronicotinonitrile. ESI-MS (m/z): 429 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-3cf0a213886b4bc085519bda7de9abdf
Source noteuspto-grants-2016_09