4-Methylpyrazole → 5-Methyl-2-(4-methyl-1H-pyrazol-1-yl)benzoic acid

HRID 61031Notes

Reaction equation

[CH3:1][C:2]1[CH:3]=[CH:4][C:5](N2N=CC=N2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8].[CH3:16][C:17]1[CH:18]=[N:19][NH:20][CH:21]=1>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N:19]2[CH:18]=[C:17]([CH3:16])[CH:21]=[N:20]2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8]

Participants

Reactant 2

HCID 34064-Methylpyrazole

HCID 532601655-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid

Product 1

HCID 625153075-Methyl-2-(4-methyl-1H-pyrazol-1-yl)benzoic acid

Procedure

The title compound was prepared following the same general protocol as described for 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid in Example A11 using 4-methyl-1H-pyrazole. MS (ESI) 217 (M+H).

Sources & evidence

ORD record: ord-a00145f67fde4a81839f039c94f7beaf
Source dataset: uspto-grants-2016_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09440982B2

Reaction notes

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