HRID610336

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CC=C3C)cc1

HCID18314553

未命名化合物

2 次

结构：CC1(C)CC=C(c2ccccc2)c2ccc(C#Cc3ccccc3C(=O)O)cc21

HCID67687635

未命名化合物

2 次

PRODUCTS

生成物

结构：CC1=CCC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21

HCID18314595

未命名化合物

PROCEDURE

实验过程

Employing the same general procedure as for the preparation of 4-[(7,8-dihydro-8,8-dimethyl-5-phenylnaphth-2-yl)ethynyl]benzoic acid (Compound 97), 37 mg (0.11 mmol) of ethyl 4-[(7,8-dihydro-5,8,8-trimethylnaphth-2-yl)ethynyl]benzoate (Compound 95) was converted to the title compound (white solid) using 23 mg (1.1 ml, 0.54 mmol) of LiOH (0.5 M aqueous solution).