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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 610450Generated: October 31, 2026

Hydrochloric Acid → HCID 86754917, compound

https://huagongshe.com/reaction/610450

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantCefadroxilHCID 47965—
ProductHCID 86754917HCID 8675491783%

Reaction Steps

The resultant crude mixture containing protected cefadroxil is worked up by treatment with a mixture of ice water and concentrated HCl. The phases are separated and Reextraction with water/HCl is carried out. The combined aqueous phases are treated with additional DMF, the solution is filtered and left overnight in a refrigerator. Crystalline cefadroxil dimethylformamide solvate is obtained, filtered off, washed with acetone and dried. Yield: 83%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05998610
Source datasetuspto-grants-1999_12
ORD IDord-5633b7250586482490bd8c9a3ba0be4e
Source noteuspto-grants-1999_12