HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 86754917, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Cefadroxil | HCID 47965 | — |
| Product | HCID 86754917 | HCID 86754917 | 83% |
Reaction Steps
The resultant crude mixture containing protected cefadroxil is worked up by treatment with a mixture of ice water and concentrated HCl. The phases are separated and Reextraction with water/HCl is carried out. The combined aqueous phases are treated with additional DMF, the solution is filtered and left overnight in a refrigerator. Crystalline cefadroxil dimethylformamide solvate is obtained, filtered off, washed with acetone and dried. Yield: 83%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05998610 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-5633b7250586482490bd8c9a3ba0be4e |
| Source note | uspto-grants-1999_12 |