HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Thenoyl chloride → 5-(N-[3-thiophenecarbonyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Thenoyl chloride | HCID 2776377 | — |
| Reactant | 3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-ylamine | HCID 10220230 | — |
| Product | 5-(N-[3-thiophenecarbonyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine | HCID 11046087 | 64.2% |
Reaction Steps
Beginning with 1.5 gm (6.5 mMol) 5-amino-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine and 1.2 gm (7.8 mMol) 3-thiophenecarbonyl chloride, 1.42 gm (64%) of the title compound were prepared essentially by the procedure described in Example 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05998622 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-3826ae619c1f4daa8b53041536dc5d2a |
| Source note | uspto-grants-1999_12 |