HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine-2-carbonyl chloride → 5-(N-[2-pyridinecarbonyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine-2-carbonyl chloride | HCID 135034 | — |
| Reactant | 3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-ylamine | HCID 10220230 | — |
| Product | 5-(N-[2-pyridinecarbonyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine | HCID 11110452 | 26% |
Reaction Steps
Beginning with 0.30 gm (1.30 mMol) 5-amino-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine and 0.34 gm (1.56 mMol) 2-pyridinecarbonyl chloride, 0.098 gm (26%) of the title compound were prepared as a crystalline solid essentially by the procedure described in Example 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05998622 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-2e734e70049b42979d15d1ab8aff2d6d |
| Source note | uspto-grants-1999_12 |