4-Fluorobenzoyl chloride → HCID 11013959, compound

HRID 610585Notes

Reaction equation

HRID 610585 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]2[C:8]([C:11]3[CH2:12][CH2:13][N:14]([CH2:17][CH3:18])[CH2:15][CH:16]=3)=[CH:9][NH:10][C:5]2=[CH:4][CH:3]=1.[F:19][C:20]1[CH:28]=[CH:27][C:23]([C:24](Cl)=[O:25])=[CH:22][CH:21]=1>>[F:19][C:20]1[CH:28]=[CH:27][C:23]([C:24]([NH:1][C:2]2[N:7]=[C:6]3[C:8]([C:11]4[CH2:12][CH2:13][N:14]([CH2:17][CH3:18])[CH2:15][CH:16]=4)=[CH:9][NH:10][C:5]3=[CH:4][CH:3]=2)=[O:25])=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 678794-Fluorobenzoyl chlorideHCID 10922730HCID 10922730, compound

Product 1

HCID 11013959HCID 11013959, compound

Procedure

Beginning with 0.015 gm (0.062 mMol) 5-amino-3-(1-ethyl-1,2,3,6-tetrahydropyridin-4-yl)pyrrolo[3,2-b]pyridine and 0.008 mL (0.068 mMol) 4-fluorobenzoyl chloride, the title compound was prepared essentially by the procedure described in Example 7. MS(m/e): 365(M+1)

Sources & evidence

ORD record
ord-4b784360773a495daa73a8b35c0be069
Source dataset
uspto-grants-1999_12
Patent number
US05998622

Reaction notes

Loading…