Benzenesulfonyl chloride → HCID 19601583, compound

Participants

Reaction Steps

Beginning with 0.40 gm (1.74 mMol) 5-amino-3-(1-methylpiperidin-4yl)pyrrolo[3,2-b]pyridine and 0.267 ML (2.09 mMol) phenylsulfonyl chloride, 0.493 gm (76%) of the title compound were prepared as an orange solid essentially by the procedure described in Example 4. An analytical sample was crystallized from aqueous ethanol. m.p.=148.1-149.7° C. MS(m/e): 371(M+1) Calculated for C19H22N4O2S: theory: C, 61.60; H, 5.99; N, 15.12. Found: C, 61.87; H, 6.26; N, 15.29.

Provenance & Evidence