Benzyl Alcohol → Benzyl 6-Bromohexyl Ether

HRID 610689Notes

Reaction equation

HRID 610689 reaction equation
[CH2:1]([OH:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]Br>>[CH2:1]([O:8][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][Br:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 244Benzyl AlcoholHCID 123681,6-Dibromohexane

Product 1

HCID 2784764Benzyl 6-Bromohexyl EtherYield 36%

Procedure

6-Benzyloxyhexyl bromide was prepared from benzyl alcohol (4.75 g, 44 mmol) and 1,6-dibromohexane (9.76 g, 40 mmol) using the general procedure given above. Yield: 36%, bp 100-105° C./torr: 1H-NMR: 1.2-1.9 (m, 8H), 3.37 (t, 4H), 4.46 (s, 2H), 7.28 (m, 5H).

Sources & evidence

ORD record
ord-13d209292332479d807dd46d35c9dd7d
Source dataset
uspto-grants-1999_12
Patent number
US05998642

Reaction notes

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